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The knob-billed duck is declining in numbers locally, but due to its wide range it is not considered globally threatened by the IUCN

T.NkadimengS

Pietrobon, D., & Moskowitz, M

(accessed 26 June 2025)

Kovalzon and Strekalova, summarizing the field in 2006, were explicit: the link between DSIP and sleep had never been further characterized, in part because of the lack of isolation of the DSIP gene, protein and possible related receptor, and the hypothesis of DSIP as a sleep factor was extremely poorly documented and still weak (Kovalzon & Strekalova, 2006)